Zepbound weight loss (obesity)
tirzepatide · made by Eli Lilly · injection (weekly)
Verified June 2026Approved forweight loss (obesity)
List price~$1,271/mo
Cheapest legitimate cash path
LillyDirect self-pay vials from ~$299/mo for lower doses (higher doses cost more). Source: GLP-1 Cost 2026 guide ↗
Good to know
Tirzepatide (dual GIP/GLP-1) has shown the largest average weight loss of the injectables.
How to pay less
- Insurance + appeal if denied usually beats any cash price.
- Medicare Part D: the GLP-1 Bridge (from July 1, 2026).
- Medicaid: status varies by state.